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Publications Summary

These are the publications from GC6 studies.

2008

Djoba Siawaya JF, Roberts T, Babb C, Black G, Golakai HJ, Stanley K, Bapela NB, Hoal E, Parida S, van Helden P, Walzl G.

An evaluation of commercial fluorescent bead-based luminex cytokine assays. PLoS ONE. 2008 Jul 2;3(7):e2535. PMID: 18596971

Garcia-Contreras L, Wong YL, Muttil P, Padilla D, Sadoff J, Derousse J, Germishuizen WA, Goonesekera S, Elbert K, Bloom BR, Miller R, Fourie PB, Hickey A, Edwards D.

Immunization by a bacterial aerosol. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4656-60. Epub 2008 Mar 14. PMID: 18344320

Mandalakas AM, Hesseling AC, Chegou NN, Kirchner HL, Zhu X, Marais BJ, Black GF, Beyers N, Walzl G.

High level of discordant IGRA results in HIV-infected adults and children. Int J Tuberc Lung Dis. 2008 Apr;12(4):417-23. PMID: 18371268

Scriba TJ, Kalsdorf B, Abrahams DA, Isaacs F, Hofmeister J, Black G, Hassan HY, Wilkinson RJ, Walzl G, Gelderbloem SJ, Mahomed H, Hussey GD, Hanekom WA.

Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response. J Immunol. 2008 Feb 1;180(3):1962-70. PMID: 18209095

Zvi A, Ariel N, Fulkerson J, Sadoff JC, Shafferman A.

Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analyses. BMC Med Genomics. 2008 May 28;1:18. PMID: 18505592

2007

Geluk A, Lin MY, van Meijgaarden KE, Leyten EM, Franken KL, Ottenhoff TH, Klein MR.

T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination. Infect Immun. 2007 Jun;75(6):2914-21. Epub 2007 Mar 26.
PMID: 17387166

Mandalakas AM, Hesseling AC, Chegou N, Kirchner HL, Zhu X, Marais BJ, Black GF, Beyers N and Walzl G.

High level of discordant IGRA results in HIV-infected adults and children. Int J Tuberc Lung Dis 2008 Apr; 12(4):417-23. PMID: 18371268

Jacobsen M, Repsilber D, Gutschmidt A, Neher A, Feldmann K, Mollenkopf HJ, Ziegler A, Kaufmann SH.
Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis. J Mol Med. 2007 Jun;85(6):613-21. Epub 2007 Feb 23. PMID: 17318616

Jacobsen M, Detjen AK, Mueller H, Gutschmidt A, Leitner S, Wahn U, Magdorf K, Kaufmann SH.
Clonal expansion of CD8+ effector T cells in childhood tuberculosis.
J Immunol. 2007 Jul 15;179(2):1331-9. PMID: 17617626

Kaufmann SH and Parida SK
(2007) Changing funding patterns in Tuberculosis. Nat Med.13(3):299-303. Review

Lin MY, Geluk A, Smith SG, Stewart AL, Friggen AH, Franken KL, Verduyn MJ, van Meijgaarden KE, Voskuil MI, Dockrell HM, Huygen K, Ottenhoff TH, Klein MR.
Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination.
Infect Immun. 2007 Jul;75(7):3523-30. Epub 2007 May 14. PMID: 17502400

Rachman H, Kaufmann SH.
Exploring functional genomics for the development of novel intervention strategies against tuberculosis. Int J Med Microbiol. 2007 Nov;297(7-8):559-67. Epub 2007 Apr 27. PMID: 17467338

Radosevic K, Wieland CW, Rodriguez A, Weverling GJ, Mintardjo R, Gillissen G, Vogels R, Skeiky YA, Hone DM, Sadoff JC, van der Poll T, Havenga M, Goudsmit J.

Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon. Infect Immun. 2007 Aug;75(8):4105-15. Epub 2007 May 25. PMID: 17526747

Sadoff JC, Wittes J.

Correlates, surrogates, and vaccines. J Infect Dis. 2007 Nov 1;196(9):1279-81. Epub 2007 Oct 2. PMID: 17922389

Weichold FF, Mueller S, Kortsik C, Hitzler WE, Wulf MJ, Hone DM, Sadoff JC, Maeurer MJ.
Impact of MHC class I alleles on the M. tuberculosis antigen-specific CD8+ T-cell response in patients with pulmonary tuberculosis.
Genes Immun. 2007 Jun;8(4):334-43. Epub 2007 Apr 12.
PMID: 17429413

2006

Baumann S, Nasser Eddine A, Kaufmann SH.
Progress in tuberculosis vaccine development. Curr Opin Immunol. 2006 Aug;18(4):438-48. Epub 2006 Jun 13. Review. PMID: 16777396

Jacobsen M, Repsilber D, Gutschmidt A, Neher A, Feldmann K, Mollenkopf HJ, Ziegler A, Kaufmann SH.
Ras-associated small GTPase 33A, a novel T cell factor, is down-regulated in patients with tuberculosis. J Infect Dis. 2005 Oct 1;192(7):1211-8. Epub 2005 Aug 24. PMID: 16136464

Jacobsen M, Repsilber D, Gutschmidt A, Neher A, Feldmann K, Mollenkopf HJ, Kaufmann SH, Ziegler A.
Deconfounding microarray analysis - independent measurements of cell type proportions used in a regression model to resolve tissue heterogeneity bias. Methods Inf Med. 2006;45(5):557-63. PMID: 17019511

Jeffries DJ, Hill PC, Fox A, Lugos M, Jackson-Sillah DJ, Adegbola RA, Brookes RH.
Identifying ELISPOT and skin test cut-offs for diagnosis of Mycobacterium tuberculosis infection in The Gambia. Int J Tuberc Lung Dis. 2006 Feb;10(2):192-8. PMID: 16499260

Kaufmann SH.
Envisioning future strategies for vaccination against tuberculosis. Nat Rev Immunol. 2006 Sep;6(9):699-704. Epub 2006 Aug 18. PMID: 16917508

Kaufmann SH, Baumann S, Nasser Eddine A.
Exploiting immunology and molecular genetics for rational vaccine design against tuberculosis. Int J Tuberc Lung Dis. 2006 Oct;10(10):1068-79. Review. PMID: 17044198

Leyten EM, Lin MY, Franken KL, Friggen AH, Prins C, van Meijgaarden KE, Voskuil MI, Weldingh K, Andersen P, Schoolnik GK, Arend SM, Ottenhoff TH, Klein MR.
Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis. Microbes Infect. 2006 Jul;8(8):2052-60. Epub 2006 Jun 13. PMID: 16931093

Nasser Eddine, A., S. Baumann and S.H.E. Kaufmann.
New Tuberculosis Vaccines Approaching Clinical Trial – An Overview. Drug Discovery Today: Therapeutic Strategies Volume 3, Issue 2, Summer 2006, Pages 113-119

Rachman H, Strong M, Schaible U, Schuchhardt J, Hagens K, Mollenkopf H, Eisenberg D, Kaufmann SH.
Mycobacterium tuberculosis gene expression profiling within the context of protein networks. Microbes Infect. 2006 Mar;8(3):747-57. Epub 2006 Jan 18. PMID: 16513384

Rachman H, Strong M, Ulrichs T, Grode L, Schuchhardt J, Mollenkopf H, Kosmiadi GA, Eisenberg D, Kaufmann SH.
Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis. Infect Immun. 2006 Feb;74(2):1233-42. PMID: 16428773

Rachman H, Lee JS, Angermann J, Kowall J, Kaufmann SH.
Reliable amplification method for bacterial RNA. J Biotechnol. 2006 Oct 20;126(1):61-8. Epub 2006 Apr 17. PMID: 16603269

Skeiky YA, Sadoff JC.
Advances in tuberculosis vaccine strategies. Nat Rev Microbiol. 2006 Jun;4(6):469-76. Review. PMID: 16710326